What Does the Bone Profile Test For? And What are Normal Test Results?

The bone profile blood test may be used to monitor a range of different bone conditions – as well as diseases that don’t directly relate to your bones at all. However, if you’re taking the test yourself, you might also be interested to hear the precise minerals for which the bone profile tests.

There are four main minerals that the blood profile measures. These are here, along with the reference ranges for each.  

  • Calcium. Primarily, the bone profile measures the calcium in your blood. This is one of the most important minerals that aids in your bone health. our normal levels of calcium are 2.2-2.6 mmol/L.
  • Albumin. This one is a protein created in the liver. However, low albumin levels are associated with lower bone density, so this test can be used to identify osteoporosis. Its normal range is 35-50 g/L, says the NHS.
  • Alkaline phosphatase (ALP). This is an enzyme, found in bone and liver cells, that is used to detect bone disorders or liver diseases. Reference ranges for the enzyme are 30-130 u/L in adults.
  • Phosphate. Phosphates are chemicals that contain phosphorus, a mineral that is crucial for bone growth. It should be between 0.74 and 1.4 mmol/L.

Finally, a bone profile may test for urea, total proteins, and globulin too.

Bone metabolism tests available

  1. Calcium
  2. Parathyroid
  3. vitamin D
  4. Inorganic phosphorus
  5. Magnesium 
  6. Anti CCP

These tests are used to help diagnose, evaluate, and monitor people suspected of having Acute Coronary Syndrome (ACS).
MARKER WHAT IT IS TISSUE SOURCE REASON FOR INCREASE TIME TO INCREASE TIME BACK TO NORMAL WHEN/HOW USED

Cardiac Troponin

Regulatory protein complex; two cardiac-specific isoforms: T and I Heart Injury to heart 3 to 4 hours Remains elevated for 10 to 14 days Diagnose heart attack, risk stratification, assist in deciding management, assess degree of damage

High-sensitivity cardiac troponin
Currently not approved in U.S. but may be soon; it is routinely used in Canada, Europe

 Same as above, just measures the same protein at a much lower level Heart Injury to heart Within 3 hours of onset of symptoms Same as above Same as above; may also be elevated in stable angina and people without symptoms and indicates risk of future cardiac events (e.g., heart attacks)

CK

Enzyme; total of three different isoenzymes Heart, brain, and skeletal muscle Injury to skeletal muscle and/or heart cells 3 to 6 hours after injury, peaks in 18 to 24 hours 48 to 72 hours, unless due to continuing injury Frequently performed in combination with CK-MB; sometimes to detect second heart attack occurring shortly after the first

CK-MB

 Heart-related isoenzymes of CK Heart primarily, but also in skeletal muscle Injury to heart and/or muscle cells 3 to 6 hours after heart attack, peaks in 12 to 14 hours 48 to 72 hours, unless new or continuing damage Less specific than troponin, may be ordered when troponin is not available

Myoglobin

Oxygen-storing protein Heart and other muscle cells Injury to muscle and/or heart cells 2 to 3 hours after injury, peaks in 8 to 12 hours Within one day after injury Used less frequently; sometimes performed with troponin to provide early diagnosis

Book Home Visit







Superior and technologically enhanced laboratory testing

Plot 38 Clive Road West, Golden City Building, Jinja - Uganda.
0393 215 000 or 0750 805 252. TOLL FREE: 0800-211-303
info@gracelaboratories.co.ug

© Copyright 2024,
Grace Laboratories,
All Rights Reserved

LinkedIn Youtube